Friday, November 29, 2019

Opera free essay sample

Opera, starting out the Baroque period, stemmed from Humanism in the Renaissance era. Opera went back to wanting to make people have a emotional response to the music they were listening to through the musical devices that they used to write the music. They were becoming obsessed again with the Greek style of music however, they wanted to make it better and so they came up with some of their own new developments for example, one device they used was the stile representative. This is Italian for representational style.Stile representative was a Tyler of singing similar to Italian monody that was then used in the very first operas. This style was used to move the plot of the opera along, it was not a full blown song however; it was more musical than normal speech. Musically the stile representative is a vocal line that gets to move freely over a basso continuo. We will write a custom essay sample on Opera or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page This style eventually turns Into our modern day recitative. Stemming off of the stile representative is monody which Is Just one voice singing with some type of accompaniment. This seems to be the basis for most of these early operas.Stemming if of both of the previous practices is the stile recitative which is pretty much the exact same thing as the stile representative. The difference between these two styles is that the stile recitative was more imitating natural speech inflections with music where the stile representative was not. Another development was known as prima practical, Italian for first practice. This referred to the style of the past, the ears perfecta or Renaissance polyphony. The pair to that Is the seconds practical, Italian for second practice. This refers to the modern style of music that was used in the singings of opera.This practical was more dissonant than the prima practical and they used such terms to distinguish the two different styles. Credit for the seconds practical goes to Claudio Monteverdi who also wrote the first major opera. The Florentine Camera was a group of elite musicians who were all associated with the royals. The Camera got together In order to figure out how to make music better and more emotional than it already was. The Camera promoted monody because one of their members, Gorillas Mel, wrote a book about the music of ancient Greece.From their promotion of monody came the other styles I discussed in the beginning of the paper. This group also gave way to intermezzi which are little musical plays and this group wanted the text to be super understandable. This eventually led to the flirts opera. Artful really did not Like the new style that came about through the beginning of opera and decided to give Monteverdi a piece of his mind. He wrote a published work describing how he felt. In this work he calls Monteverdi incompetent because of how he was writing the music. Artist wanted to keep all the rules of the prima practical intact and thought that it did not get any better than that. He believed that if they were not written in the style of the renaissance composers then they do not have a the second practice were going to make fools of themselves. Artist also says that this compositions are written by ignorant people and that these composers are kept in a state of intellectual darkness. Monteverdi responds to Artists statement by saying that he can over ride the rules because the most important thing is the text ND the expression of said words.He says that it is written in that style on purpose and not out of ignorance. Monteverdi pretty much responds with the baroque philosophy of music and that the goal was, what the article called imitation Della natural or the imitation of reality. Which did end up a huge success and he continues on to give an example of the emotion he wanted and how he planned on getting it. The elements above are conveyed in the opera LOreal through the music. Also a little bit through the emotion on the faces of the singers and through some word notating a little bit.I think that the word painting is effective and also the style. You can tell for sure that it is in the seconds practical style. However, when Just hearing the opera I think the aria and the recitative become less effective I think to a person not musically trained. I think that if someone was Just listening to the opera they Mould not be able to tell the difference between the two section of the opera. The music we have been listening to up to this point in time has been very polyphonic and very constant not put on stage. The music of LOreal is monadic although it does have a few polyphonic parts. This music also has a lot more dissonance to better create the darker moods and the people can not only listen to what the music is trying to portray but can also see it on the stage and understand everything better. They do not have to guess as to what is going on. It is all laid out in front of them or sis versa they do not have to guess as to what the people on stage are trying to portray because they have the simple music lines underneath them singing.

Monday, November 25, 2019

Free Essays on 180 Poems

back in the ladies face in a way. She tells him to give her orders and he’s okay then tell me to lift my right arm. Pretty much twisting what she says, but stilling doing what she says. It also portrays the idea of rather being a follower than being a leader. Showing it is easier to do what someone else tells you to than to think up your own ideas and telling them what to do. In the poem the lady was probably also testing his patience, by not saying anything and that’s why when he asks "what next" that’s why she says now its your turn to give the orders, showing him just to wait. In the end though the poem is simply about giving and taking directions. My deciphering of this poem shows you can look deep and see the many meaning or you can just look at the surface and just see the main point. It also shows that poems can be interpreted differently depending on the reader. Peter Cherches could have had totally different ideas about this poem. I like this poem because of it’s sense of humor and bit of saucy sarcasm. Many of the poems that I had looked at on this website had no depth, no hidden meaning, not saying this was an extremely deep poem. It was just more interesting than most of them. Another poem I also liked was "The Panic Bird" by Robert Phillips. It included symbolism and feelings. The feeling were of fear and panic which the author hates, yet they always come back. The bird symbolizes the fear, which he hates and he describes it in depth throug... Free Essays on 180 Poems Free Essays on 180 Poems Poems are a way to express people’s ideas and reflect on their feeling. They have many different depths and themes. Poetry can reveal a lot about the person writing it. It can show their sensitivity, sense of humor, what they have gone or their thoughts on life. The poem I choose from poetry 180 was "Lift Your Right Arm" by Peter Cherches. This poem uses the idea of giving and taking orders, but it turns it into something funny. It is funny because he is throwing the words back in the ladies face in a way. She tells him to give her orders and he’s okay then tell me to lift my right arm. Pretty much twisting what she says, but stilling doing what she says. It also portrays the idea of rather being a follower than being a leader. Showing it is easier to do what someone else tells you to than to think up your own ideas and telling them what to do. In the poem the lady was probably also testing his patience, by not saying anything and that’s why when he asks "what next" that’s why she says now its your turn to give the orders, showing him just to wait. In the end though the poem is simply about giving and taking directions. My deciphering of this poem shows you can look deep and see the many meaning or you can just look at the surface and just see the main point. It also shows that poems can be interpreted differently depending on the reader. Peter Cherches could have had totally different ideas about this poem. I like this poem because of it’s sense of humor and bit of saucy sarcasm. Many of the poems that I had looked at on this website had no depth, no hidden meaning, not saying this was an extremely deep poem. It was just more interesting than most of them. Another poem I also liked was "The Panic Bird" by Robert Phillips. It included symbolism and feelings. The feeling were of fear and panic which the author hates, yet they always come back. The bird symbolizes the fear, which he hates and he describes it in depth throug...

Friday, November 22, 2019

About horror movies Essay Example | Topics and Well Written Essays - 1000 words - 1

About horror movies - Essay Example m the Japanese filmmaker called Miike, whose films provide prototypical examples of â€Å"Asia Extreme† other directors such as Kim Ki-duk and Park Chan-wook have expanded the category by rendering ultra-violet narratives set against serene portrayals of the troubled psyches of doomed protagonists. Following the success of magic lantern shows in the late 1890s, the first cinematograph was introduced into Japan in 1897. In 1899, the first Japanese film was shown at the Kabuki-za, Tokyo. Kabuki, one of the foremost traditional Japanese theatrical forms, would provide rich material for the burgeoning art of the visual image and would become the template for many Japanese horror films since. Tales of horror and monstrosity have long concerned themselves with notion of hybridity in their exploration of those regions where categories fail to maintain their integrity. Ghosts, for instance, are their very liminal entities negotiating the supposedly unbridgeable gap between the world of the dead and the realm of the dead. In addition, monsters are perpetual scramblers of social codes, often troubling the nebulous (Gladwin). There is always something nasty about horror movies that speaks instinctively and directly to humans. Evolutionary psychology that has undergone evolution for millions of years has caused the human mind to be ingrained to certain triggers of fears. For example, there has been fear of dark places where predatory animals might be laying waiting for the prey. There is also fear of animals that tend to have sharp teeth since they might easily make a meal out of us. Such fears have been engrained into the human developmental psychology to an extent that research shows that children can easily spot a snake on a computer’s screen compared to how they can spot a flower (Gladwin). This idea explains the shape of monsters commonly used in horror movies; that is, creatures that have sharp teeth or appear like snakes. The fear of being eaten alive has always

Wednesday, November 20, 2019

Assignment Essay Example | Topics and Well Written Essays - 2500 words - 4

Assignment - Essay Example There is an established communication between Adam (man) and God (divine). Adam is seen stretching his hand reluctantly and loosely to receive what God is presenting to him. God is trying to transmit some sought of divinity to man. This is being attempted by bringing their fingers as close as possible but it is clear the fingers do not establish a contact. This could be the impossibility of God and man being into contact. The story is biblical though and it has it that after Creation of Adam, God breathed life into him. In the bible there is nowhere we are told that there was a lot of resistance in the process. However, in the creation of man, the work presents an interesting fact (Kleetus, 2005). God is seen trying to reach Adam with all his might. He is stretching his index finger to touch that of Adam. It seems there is a resistance in form of a wind, which is trying to deny him a chance to communicate to his creation. The presence of a wind-like force is depicted in the direction of God’s legs and those of the angels surrounding him. The implication from the figure here is that God is trying with all his might to touch and transmit his mightiness to hid creation amidst a strong opposing force. On the other hand, dam does not seem to have the energy and effort to reach to God. Adam is relaxed and while God is using his right hand to reach him, Adam is using his right hand to support his lazily leaning body and reluctantly uses his left hand to respond to God’s attempt to reach him. The left hand has to be supported by his left leg knee for that case. Adam’s body is leaning against God and it seems he is not willing enough or putting enough effort to make the divine connection with God. The body language of the two is totally different and while one is responding with strength to establish a connection, the receiver is not so much putting an effort to receive. A closer look at the index fingers of the two subjects in

Monday, November 18, 2019

Social problem Essay Example | Topics and Well Written Essays - 1500 words

Social problem - Essay Example To address this issue, the paper will draw on a variety of different sources as well as give some personal opinions on the matter. There is little question that drugs can play a very positive role in our modern society. Drugs are often prescribed or taken in moderation to help our physical health, and in this respect one can consider drug use to be beneficial to our societal well being. According to the World Health Organization (1969) a drug is in its most basic terms, a substance that can be absorbed into the body to modify a bodily function. In this respect one could consider any number of chemically engineered and naturally occurring substances as being classified as a drug. However in a more common context and for the purpose of this paper, the focus will be on drugs that are taken for recreational purposes to the determent of one’s personal health (Or wellbeing) or to those around the drug taker in question. For the purpose of this paper the focus will be on more traditional drugs such as alcohol, cannabis, opiates, barbiturates, etc. It should be noted that many of thee drugs are legally obtained, either over the counter, or through prescription yet still maybe detrimental. There are many substances such as coffee which technically meet the definition of being a drug and may be detrimental to one’s health but in the broadest sense these substances are not as detrimental to society as a number of other more powerful narcotics. Why are drugs considered a societal problem? In many circumstances people can take drugs recreationally and not harm themselves. So it is the case that a drug such as alcohol in the hands of most people does not represent a serious threat to society or one’s health. However it is the case that some people do negatively respond to the stimuli brought about from alcoholic beverage consumption and engage in behavior that

Saturday, November 16, 2019

Liver Functions, Anatomy and Diseases

Liver Functions, Anatomy and Diseases Sandra Marais Nikita Wiggil Charne Scott Chante Wiese   Sue-May van der Westhuizen Stephanie Willows Contents (Jump to) Introduction The Anatomy and function of the Liver Definition and description of the disease Fatty Liver Disease Symptoms PATHOPHYSIOLOGY AND ETIOLOGY OF FATTY LIVER DISEASES: Treatment and prevention Introduction The Anatomy and function of the Liver Anatomy is the science of the structure and shape of entities. It is important for the knowledge of hepatic anatomy and surgery. The liver is one of the largest organs of the human body after the skin it is the second largest. The liver is the largest gland in the human body, with an average weight of 1500g. The transverse measurements ranges between 20 and 22,5cm, its vertical measurements (close to its right/lateral surface) between 15 and 17,5cm and its antero-posterior diameter between 10 and 12,5cm. Its measurement, from opposite the vertebral column, is reduced to roughly 7,5cm. It is found underneath the diaphragm -in the right upper abdomen, mid abdomen as well as in parts of the left upper abdomen. The shape of the liver generally has the form of a wedge or a prism. According to Synington the shape resembles that of a right-angled triangular prism with the right angle rounded off. Its base faces the right and its apex to the left, the colour of the liver is dark reddish brown it has a soft degree of density, it contains a large amount of vessels and is very brittle. In an adult, it is smaller than in a fetus. In the later (side) it contributes roughly one thirty-six of the body weight. In the former (side) it contributes roughly one-eighteenth of the body weight. The liver has three surfaces namely the superior (Facies superior), inferior (Facies inferior/ visceral surface) and posterior (Facies posterior). The posterior surface is divided from the superior surface by a sharp margin. The superior surface attaches itself to the diaphragm as well as the anterior abdominal by the falciform ligament (ligamentum falciform hepatis). The falciform ligament separates the liver into a right lobe (lobus hepatis dexter) and a left lobe (lobus hepatis sinister). The right lobe is larger than the left. Five fossae divide the inferior and posterior surfaces into four lobes. The fossae are arranged like the letter ‘’H’’. The left limb of the H is divided into what is known as the left sagittal fossa (fossa sagittalis sinistra/longitudinal fissure) consisting off the fossa of the umbilical vein and the fossa for the ductus venosus. The right limb of the H consists of the fossa for the gall-bladder (fossa vesicà ¦ felleà ¦) and th e fossa for the inferior vena cava (fossa venà ¦ cavà ¦). The two limbs of the H surfs as a transverse fissure- the porta (porta hepatis/transverse fissure). The superior surface is part of is part of the left and right lobe. This surface is convex. The middle part is found behind the xiphoid process and it makes contact with the abdominal wall. It is entirely concealed by peritoneum, with the exception of the line of attachment of the flaciform ligament. The inferior surface is concave. It is aimed downward, backward as well as to the left. The surface is infused in peritoneum- the only parts that are without it, is where the gall-bladder and the liver attaches as well as at the porta hepatis. The posterior surface has a curved surface and is broad on the right, but narrow on the left. The diaphragm is attached with a triangular and coronary ligament that intertwine connective tissue, it leads to the intimate connection of the inferior vene cava that is connected with hapatic veins that holds up the posterior part of the liver. The abdominal viscera full the abdomen, where the muscular walls are in a state of tonic contraction. The superior surface of the liver fits under the diaphragm surface, so that the pressure is enough to hold the diaphragm. The lax falciform ligament creates no support for the lateral displacement and the latter creates negative pressure that is held up in the thorax (Gray, Henry. Anatomy of the Human Body. PHILADELPHIA: Lea Febiger, 1918; Bartleby.com, 2000. www.bartleby.com/107/. [DATE of Printout].) Functions of the liver The liver receives blood from two main sources: 30% is received from the hepatic arteries and 70% is received from the hepatic portal vein. The hepatic portal vein receives blood from the stomach, intestines, pancreas and spleen; which is then carried to the liver through the porta hepatis. All nutrients are absorbed by the small intestine, all nutrients reaches the liver by this route except for lipids. Arterial blood bound for the liver exists the aorta ant the celiac trunk. These arteries deliver oxygen and other materials to the liver. (SALADIN, p. 975-977) Digestion Liver produces bile; which is a mixture of water, bile salts, cholesterol and pigments of bilirubin. Bile is produced by hepatocytes in the liver. Bile passes through the bile ducts and is stored in the gallbladder. Fats are emulsificated by bile. Large fat clumps are turned into smaller pieces which makes it easy for the body to digest. Old worn oud red blood cells are destroyed by Kupffer cells in the liver. Kupffer cells pass their components to the hepatocytes. Haemoglobin is the red oxygen-carrying pigment of red blood cells, haemoglobin is metabolized into heme and globin components. Energy for the body comes from globin protein. Metabolism Liver is responsible for metabolizing carbohydrates , lipids and proteins into biologically useful materials. Blood entering the liver through the hepatic portal vein is rich in glucose from digested food. Some of this glucose is absorbed by hepatocytes. The glucose is stored as the macromolecule glycogen. Homeostasis is maintained by the absorption and release of glucose by the hepatocytes, it helps protect the body from spikes and drops that can be dangerous in the blood glucose level. Hepatocytes absorb and metabolise fatty acids to produce energy in the form of ATP. Through gluconeogenesis the hepatocytes convert glycerol and other lipid components into glucose. Cholesterol is a lipid which can also be produced by hepatocytes and gets excreted from the body as a component of bile. Amino acids is a component from dietary proteins. Amine groups are removed from the amino acids, by the hepatocytes, which is further converted into ammonia and urea. Urea can be excreted in urine as a waste product. Urea is less toxic than ammonia. Detoxification Hepatocytes cells of the liver monitor the contents of the blood and toxic substances are removed before they reach the rest of the body. Alcohol and drugs are metabolised into their inactive metabolites by the enzymes in hepatocytes cells. Storage Nutrients, vitamins and minerals obtained from the blood passing through the hepatic portal system are stored in the liver. Homeostasis of blood glucose is maintained by the storage of nutrients. Vitamins such as A, D, E, K and B12 is stored in the liver. Minerals such as iron and copper are stored in the liver. Production Vital protein components of blood plasma such as prothrombin, fibrinogen and albumins are produced by the liver. Prothrombin and fibrinogen proteins are factors involved in the formation of blood clots. Albumins maintain the isotonic environment of blood. Immunity Bacteria, fungi, parasites, worn out red blood cells and cellular debris are captured and digest by Kupffer cells. Large volumes of blood are cleaned very quickly by Kupffer cells due to the large volumes of blood passing through the hepatic portal system. (www.innerbody.com/image _digeov/card10-new2.html) American journal of Physiology: Gastrointestinal and Liver Physiology : physiology and pathophysiology of apoptosis in epithelial cells of the liver; pancreas and intestine. By Blake. A. Jones ; Gregory. J. Gores. Published 1 December 1997 (vol.273. no.6, G1174-G1188) Definition and description of the disease Fatty liver disease â€Å"Non-alcoholic fatty liver disease (NAFLD) is a clinical and pathological syndrome.† (Zeng, et al., 2008) The main feature of NAFLD is the swelling of the (liver cells) hepatocytes because of pathological factor, alcohol excluded, that injure the liver. NAFLD is ranged from fatty liver alone to steatohepatitis, steatonecrosis and non-alcoholic steatohepartitis (NASH). (NASH) is only a stage in non-alcoholic fatty liver disease. NAFLD may have the potential to progress into cirrhosis and liver failure.† Liver –biopsy features include steatosis, mixed inflammatory cell-infiltration, hepatocytes ballooning and necrosis, glycogen nuclei, Mallory’s hyaline and fibrosis.† (Angulo, 2002) According to Jansen (2004) NASH is an under diagnosed liver disease characterized by steatosis, necroinflammation and fibrosis. NASH can possibly develop into cirrhosis and hepatic cellular carcinoma. NASH incorporate mixed acute and chronic lobular inflammation, zone 3 perisinusiodal fibrosis and ballooning (Brunt, et al., 1999). Alcoholic liver disease. Alcoholic liver disease (ALD) includes a variety of spectrum of injury that can be from simple steatosis to frank cirrhosis. There are 3 groups of histological stages of ADL. Fatty liver or simple steatosis, alcoholic hepatitis and chronic hepatitis with hepatic fibrosis or cirrhosis. ALD can be caused by different types of factors including dose, duration and type of alcohol consumption and risk factors like obesity iron overload ect. Fatty Liver Disease Symptoms Non-alcoholic fatty liver disease causes no signs or symptoms that can be noticed but when it is noticed, it show signs of: Fatigue Pain in the right upper abdomen Weight loss. Inflammation and scarring of the liver Possible progression to liver failure. Symptoms consists of four (4) stages namely Simple fatty liver disease ( steatosis), Non-alcoholic Fatty liver Disease (NAFLD), Fibrosis And Cirrhosis. Simple fatty liver (Steatosis)- There are no clear symptoms and it can only be discoverd by an abnormal blood test result. Non-alcoholic Steotohepatitis (NASH)- It is the most aggressive form of this condition, it causes the liver to become inflamed creating a dull or aching pain in the top right abdomen, covering the lower side of the ribs. There may be no signs of any symptoms at all and it can only be discovered by specialized testing. Fibrosis- Constant inflammation in the liver which leads to the formation of scar tissue. Cirrhosis- Over a long period of time, it creates inflammation which can lead to the loss of liver function- which may lead to creating primary cancer. ALCOHOL-RELATED (ARLD) It shows no symptoms until the liver has already been severely damaged and it causes symptoms such as: Feeling sick, weak or tired Loos of weight Loss of appetite Jaundice- the yellowing of the eyes and skin The swelling of the stomach and ankles Confusion or drowsiness The excretion or the vomiting of blood. Alcohol related fatty liver disease is constantly diagnosed because of other conditions or other tests. PATHOPHYSIOLOGY AND ETIOLOGY OF FATTY LIVER DISEASES: Fatty Liver Disease encompasses two over head segments, namely Alcoholic Liver Disease and Non Alcoholic Liver Disease. ALCOHOLIC LIVER DISEASE (ALD) Alcoholic Liver Disease (ALD) encompasses the manifestations of the liver that is caused by the over consumption of alcohol (ethanol). It includes Fatty Liver, Alcoholic Hepatitis, and Chronic Hepatitis with liver cell fibrosis or cirrhosis.*1 Ethanol metabolization takes place in the liver. There are two main pathways of alcohol metabolism, namely alcohol dehydrogenase and cytochrome P-450 (CYP) 2 E1. The first pathway works as follows: Firstly ethanol is metabolized by Alcohol dehydrogenase (ADH) into Acetaldehyde in the cytoplasm. The second phase occurs in the smooth Endoplasmic reticulum of mitochondria, where Acetaldehyde is further metabolized by Aldehyde dehydrogenase into acetate. Acetate is then finally oxidized into carbon dioxide (CO2) and water. CYP 2E1 also converts ethanol into acetaldehyde (OShea, et al., 2010). Liver damage occurs in a few mutually related pathways: Acetaldehyde can form hybrid-adducts with reactive residues acting on proteins or small molecules, mediating lipid peroxidation and nucleic acid oxidation. (French, et al., 1984) During further metabolization of alcohol, Nicotinamide Adenine Dinucleotide (NAD) is reduced. This causes a shift in the NADH/NAD ratio. A higher NADH (reduced form of NAD) concentration increases the production of fatty acids, while lower concentrations of NAD result in decreased fatty acid oxidation. This altered ratio impair the metabolization of carbohydrates and lipids, resulting in the diversion from gluconeogenesis to ketogenesis and fatty acid synthesis. The liver cells compound the fatty acids to glycerol to form triglycerides. These accumulating triglycerides result in fatty liver. This leads to oxidative stress, which plays a pivotal role in ALD development. (French, et al., 1984) Furthermore, Acetaldehyde interacts through covalent binding with reactive residues of proteins found on the membranes of liver cells. This binding results in the formation of stable protein by-products which have been shown to be immunogenic. Tissue damage and ALD may be caused by this, because the neo-antigens may induce an immune reaction with anti-body production. CYP 2 E 1, when exposed to chronicle alcohol use generates free radicals through the oxidation of Nicotinamide Adenine Dinucleotide phosphate (NADPH) to NADP (OShea, et al., 2010). This exposure activates hepatic macrophages, also known as Kupffer cells, which leads to Tumor Necrosis factor-alpha (TNF-alpha). The production of reactive oxygen species (ROS) is increased by the mitochondria, which in turn was induced by the TNF-alpha. This also promotes oxidative stress, which leads to hepatocytes necrosis and apoptosis. Many alcoholics have a condition of malnutrition. The deficiency in anti-oxidants, such as vitamin E, only worsens the necrosis and apoptosis. Free radicals initiate the oxidative degradation of lipids, which causes inflammation and liver tissue becomes scarred. Although the over consumption of alcohol is the primary cause of ADL, it is not always a pre-requirement for ALD development. It is important to understand the mechanisms of liver damage. When liver cells are exposed to alcohol, ATP synthesis is reduced and the activity of mitochondrial complexes is depressed. This causes energy metabolism of liver cells to be severely weaker and results in tissue damage. Metabolization of ethanol takes place in the centrilobular area of the liver lobule. Hypoxia alters energy metabolism, therefore centrilobular hypoxia can also be responsible for liver injury. The pathophysiology of alcoholic liver disease is very complex and further in depth investigation to understand the disease and how to treat it is being done. NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD) Non-Alcoholic Fatty Liver Disease is an over arching term for a variety of conditions associated with fat depositions in liver cells. NAFLD ranges from Simple fatty liver to nonalcoholic steatohepatitis (NASH), to fibrosis and cirrhosis. The first stage of NAFDL is simple fatty liver or steatosis. It is considered harmless and only consists of a fat build up in the liver. The second stage, Nonalcoholic steatohepatitis is more serious, but not many individuals progress to this state from simple fatty liver. Two liver insults may lead to the development of NASH. With the first insult or hit, macro-vesicular steatosis (abnormal retention of lipids within a cell) occurs as a result of an excessive amount of triglycerides accumulating in the liver. The cause of triglyceride accumulation can result from excessive importation of free fatty acids from adipose tissue.*5 The accumulating lipids in the liver cells seem to be caused by insulin resistance. Insulin resistance leads to changes in the livers enzymatic pathways that control free fatty acid uptake, synthesis, degradation and the secretion of free fatty acids. A crucial paradox arises: the liver maintains its liver lipid metabolization, but carbohydrate metabolism is weakened or damaged. Hepatic steatosis caused by these factors can result into diminished hepatic free fatty acid oxidation, more hepatic lipogenesis or fewer lipids are secreted from the liver. Along with insulin resistance, obesity plays an important role in the development of NAFLD. These alterations make the liver sensitive for the second insult or hit, which is an inflammatory response and further liver damage (Carey, et al., 2013). Toxic inflammatory proteins are secreted by the cytokines in the liver.*6 Hepatocyte apoptosis, an organized form of cellular death, is a leading component of the second insult of NAFLD progression. Oxidative stress and resulting lipid peroxidation are involved in the progression of NAFLD to NASH. The term â€Å"oxidative stress† is frequently used to describe the imbalances in redox couples. *7 This metabolic reaction produce too much reactive free radicals called reactive oxygen species (ROS). This process usually occurs in the mitochondria. Lipid peroxidation can lead to changes in the cell membrane fluidity and these alterations cause tissue damage. Fibrosis is the third stage of NAFLD. NASH develops to form fibrosis if it is not treated. Fibrosis occurs where chronicle inflammation in the liver results in the formation of fibrous scar tissue around hepatic cells and blood vessels. The liver still functions normally, because there is still enough healthy tissue. The forth and most severe stage of NAFLD is cirrhosis. During this stage lots of scar tissue develops. This causes the liver to shrink and change morphologically. The damage caused by cirrhosis is permanent and cannot be saved or reversed. The progression of cirrhosis is slow, but it ultimately causes the liver to stop functioning.*8 Treatment and prevention Basic therapy: you have to work out a strategic plan of the intake of calories and adjustment of diet constitution. Medium aerobic exercise and the changing of some life styles and behaviour. Weight reduction: The most important fact of weigh reduction is not the amount of weight loss but how the weight is lost. Losing weight rapidly may increase portal inflammation and fibrosis. A relatively safe goal is to lose about 1.6kg per week. Liver transplantation: For some patients liver transplantation is recommended. Metabolic states should be examined before the transplantation. A BMI >40kg lm2 is a contrain dication (Zeng, et al., 2008) Abstinence: This is a very important therapeutic intervention for patients that have ALD. Abstinence helps to decrease portal pressure and lower progression to cirrhosis.

Wednesday, November 13, 2019

Body Language :: essays research papers

What is Body Language?Definition: Body Language is communication through gestures or attitudes. (<a href="http://click.linksynergy.com/fs-bin/stat?id=pcZ8g7DjAzA&offerid=6424&type=2&subid=0&url=http%253A//search.borders.com/fcgi-bin/db2www/search/search.d2w/Details%253F%2526mediaType%253DBook%2526prodID%253D3805147" >Webster's Dictionary<IMG border=0 alt=icon width=1 height=1 src="http://ad.linksynergy.com/fs-bin/show?id=pcZ8g7DjAzA&bids=6424&type=2&subid=0" >, 1997)Why is it important for teachers to know and use?Most people remember more of what they see than what they hear. We retain vivid images of facial expressions and body behavior.Body language usually dose not lie. We can build trust with our students by showing them that our actions will be in sync with our words.Alert teachers watch their students' movements, actions, and emotions and use what they see to adjust their teaching methods to be effective with their l essons.By being alert to student behaviors, teachers can more easily predict and deter inappropriate behavior before it becomes a problem. Teachers need to be able to control their own body language so they can be in charge of the message they want to portray to the students. They can send out positive body language messages to promote positive interaction between her/himself and the students and between students and other students.Modeling positive body language is important because body language can be very contagious.Issues that contribute to one's use of body language:culture physical size gender mood past experiences age position Examples for the classroom:</bAlways observe the students' body language and be able to detect boredom. By being alert to students' body language messages you are more likely to meet their needs and interests even if they may not verbalize them. Use direct eye contact with your students. This is one of the most important nonverbal teaching skills. L ook directly at the student (not at their hair, shoulder, what they are wearing). Looking any place else is too distracting for them. Do not make it a habit to stay behind or around your desk all of the time. Whether they realize it or not, some teachers use their desk as a wall of protection or symbol of authority in the classroom.

Monday, November 11, 2019

A Christmas Story essay

A CHRISTMAS STORY A Christmas Story is an American comedy and family movie. The release date of the movie is 18 November 1983 in the United States of America. It’s about the child, Ralphie Parker who wanted to get a Red Ryder carbine-action 200-shot range model air rifle from Santa in the Christmas and got the respond of â€Å"You'll shoot your eye out,† from his parents. It was directed by Bob Clark. In addition, the movie is based on the novel â€Å"In God We Trust, All Others Pay Cash† which is written by Jean Shepherd.Jean Shepherd is narrator of the movie and he voiced Ralphie’s adult voice as well. In the movie there are three actors that were starring in the movie. The most prominent character is Ralphie (Peter Billingsley). I think Peter Billingsley played his role in the movie; because he seemed like the most wanted thing that he wanted was Red Ryder. Also, Peter Billingsley is a member of Hollywood so he played in many movies. Ralphie’s fa ther called The Old Man (Darren McGavin), and Ralphie’s mother (Melinda Dillon) were starring in it.In the movie, Ralphie, his brother and his friend was tortured by Scut Farkus (Zack Ward) and his friend Grover Dill (Yano Anaya). A day, Miss Shields who was the teacher of Ralphie wanted to write an essay about what they wanted to get in Christmas. Ralphie wrote an essay about Red Ryder bur he got C+ from his essay. In the one of the most important events in the movie, for unusual Ralphie’s mother wanted Ralphie to help his father to change a flat tire. While Ralphie was helping his father, he dropped screws of the tire and he said a bad word and he was punished.In the other event Scut Farkus threw a snowball to Ralphie and Ralphie beat him up instead of running away but he could not to be punished because of his mother. At the end of the movie, â€Å"I can’t say what happened at end of the movie, watch and see,† say the writer of this essay. If you want to know is that movie if worth for watching or not, this movie is shown 24-hour in the Christmas day by TBS which is a cable channel of the USA. Watch and have a good time with your family.

Saturday, November 9, 2019

Age of American Imperialism essays

Age of American Imperialism essays During the late nineteenth and early twentieth centuries, America decided to throw its hat in the ring for expansion. It pursued an aggressive policy of expansionism, extending its political and economic influence around the world. That era in the history of the United States is called the Age of American Imperialism. Many countries were continuing to set up colonies on islands currently occupied by barbarians, heathens, and cannibals. These countries believed that they had the god given right to take over their lives and force them into Christianity. After being commanded to give up all of their traditions and their way of life, they were put to work in factories for minimal wages and zero respect. America somehow saw this as a good thing and decided to take control of the Philippines, Hawaii, Guam, Puerto Rico, and Cuba. The United States was selfish and thought that they and only they knew what was best for those countries. So because America was stronger than others it ran over their nations and reformed them to their own liking. This is how countries were formed and unformed, so does this mean that you can take a toy from your little brother just because you are bigger? Yes, but just because you can doesnt mean you should. The United States made excuses for starting the war to justify their taking over of the little nations. But when you look back at it it seems like they were looking for a reason to go to war. The need for expansion was in their blood and they couldnt look past the greed and see the lives of the people in the way of their conquest. In my opinion, the United States thought it was bigger and better than every other nation, even though it was still one of the youngest countries. America had grown selfish and conceited, it saw what it wanted and did whatever it took to get it from its rightful owners. They even broke their own treaty, the Monroe Doct ...

Wednesday, November 6, 2019

Free Essays on Roman Buildings

Roman Architecture by Ryan Huguenin During the 2nd century BC the Romans, in conquering North Africa, Greece, Anatolia, and Spain, absorbed the architectural traditions of those areas (most significantly that of Greece), to which they added the constructional skills of the Etruscans, their immediate neighbors in central Italy. The most significant achievements of the Romans were in their technology of building, their use of a much wider range of materials (including concrete, Terra-Cotta, and fired bricks), and their refinements of the arch, vault and dome, all of which had been pioneered by the Etruscans. Roman temples generally remained modeled on those of Greece, with the common addition of a high plinth (base or platform) and the frequent omission of the side and rear columns. Roman civic monuments included a number of building types of unprecedeted size and complexity, which could not have been built using the Greek beam-and-column construction system. The aqueduct, thermae, basilica, theater, triumphal arch, amphitheater, circuses, and palaces involved enclosing much larger spaces or bridging much greater distances than could be achieved by the use of timber or stone beams. The Roman use of domed construction in mass concrete is best represented by the well-preserved Pantheon in Rome (constructed AD 120-24), which subsequently became a Christian church. Later Roman or early Christian churches, however, generally took their form from the basilica, whose central nave, side aisles, Triforium, and apsa became characteristic features of the Romanesque and Gothic church. Emperor Constantine I built huge basilican churches at all the major Christian sites in the Roman Empire in the 4th century, thus firmly establishing the basilica as the predominant form of Christian church architecture. (Ward-Perkins, 1977). According to much of my pertinent research, probably the clearest picture of Roman architecture can... Free Essays on Roman Buildings Free Essays on Roman Buildings Roman Architecture by Ryan Huguenin During the 2nd century BC the Romans, in conquering North Africa, Greece, Anatolia, and Spain, absorbed the architectural traditions of those areas (most significantly that of Greece), to which they added the constructional skills of the Etruscans, their immediate neighbors in central Italy. The most significant achievements of the Romans were in their technology of building, their use of a much wider range of materials (including concrete, Terra-Cotta, and fired bricks), and their refinements of the arch, vault and dome, all of which had been pioneered by the Etruscans. Roman temples generally remained modeled on those of Greece, with the common addition of a high plinth (base or platform) and the frequent omission of the side and rear columns. Roman civic monuments included a number of building types of unprecedeted size and complexity, which could not have been built using the Greek beam-and-column construction system. The aqueduct, thermae, basilica, theater, triumphal arch, amphitheater, circuses, and palaces involved enclosing much larger spaces or bridging much greater distances than could be achieved by the use of timber or stone beams. The Roman use of domed construction in mass concrete is best represented by the well-preserved Pantheon in Rome (constructed AD 120-24), which subsequently became a Christian church. Later Roman or early Christian churches, however, generally took their form from the basilica, whose central nave, side aisles, Triforium, and apsa became characteristic features of the Romanesque and Gothic church. Emperor Constantine I built huge basilican churches at all the major Christian sites in the Roman Empire in the 4th century, thus firmly establishing the basilica as the predominant form of Christian church architecture. (Ward-Perkins, 1977). According to much of my pertinent research, probably the clearest picture of Roman architecture can...

Monday, November 4, 2019

Individual Project Essay Example | Topics and Well Written Essays - 1000 words - 3

Individual Project - Essay Example ransactions between the fifty states in the USA; the provisions in the Constitution under Article 1, section 8 may be seen to have achieved the same objective. For example, Section 8 specifically seeks to â€Å"regulate commerce with foreign nations and among several states and with the Indian tribes†. (www.topics.law.cornell). Moreover, it also sets out the distribution of powers among the centre and the states, by setting out the arming and disciplining of the militia as the province of the central government while the appointment of the officers and the training of the militia are to be reserved by the States. In this way, this part of the Constitute sought to provide some form of overall regulation of trade and commerce occurring between the different states. Since this section also sets out the principles of borrowing and coining money as well as fixing standards and providing for punishments of illegal commerce activities such as counterfeiting of money, it did provide a n overall system of governance in the area of commerce, which makes it the effective precursor of specific legal provisions such as the UCC and UCITA. 2. Article 2 of the UCC specifically deals with the rules regulating the formulation of contracts and the procedures association with the repudiation of contracts and any breach that occurs (Rumbaugh, 2004). As opposed to this, the UCITA is specifically formulated to regulate e-commerce and computer associated transactions. The UCC also has a more pervasive role because it deals with a much wider range of issues that have been found to be relevant in contract and have been applied over the years, such as consideration, breach of contract, the battle of forms and similar issues, which allows it to play a more pervasive role. As opposed to this, the UCITA poses an entirely different set of regulatory issues which arise in the context of the technological environment. These issues are still developing, such as software piracy, difficulties in

Saturday, November 2, 2019

DISSERTATION--what motivation methods are used in the hotels in Essay

DISSERTATION--what motivation methods are used in the hotels in Sheffield to motivate part time university students who work in the frontline - Essay Example The insinuation of this add to is further indestructible as international students, when spoken as a amount of the total number of students enrolled in hospitality course universities in Sheffield, rose from5.5 percent in 1991 to 9.6 percent in 1997 (Ballard, B. and J. Clanchy 1997). Throughout this period so, universities in Australia, Canada, USA, UK experienced an internationalisation of their action; together in terms of the number of worldwide students studying intercontinental higher education programmes, and an add to in the width of international students, with around one in ten of the total enrolment make overseas. Frequently, the prevalence of international students that study for an Australia, Canada, USA, UK requirement start from Asia. Dobson et al. state that: Moreover, for part time university students studying human resource management (HRM) as a core subject, chapter will serve as a textbook at higher levels of undergraduate study and postgraduate/Masters study. For business management students studying HRM as a core subject or an option, this text will serve as secondary/further reading for motivation methods. As a sectoral source it builds upon introductions in organizational behaviour, people management or employee relations, and will be useful at higher undergraduate and post-graduate/Masters/Masters in Business Administration (MBA) levels. Social science students may also be interested in the research, as industrial relations and the employment relationship of part time students with motivation are very important dimensions of the sociology of work. For them this text will represent a rich source of information on contemporary characteristics of service sector work that can exemplify theoretical sociological perspectives, such as fragmentation and feminization of labour, and inform debates on labour process theory. Here the chapter will provide secondary/ further reading on optional courses (Barron, P. and C.